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Developmental Biology and Cancer by Gisele M. Hodges

Title Developmental Biology and Cancer
Author Gisele M. Hodges
Publisher CRC Press
Release 1993-09-27
Category Science
Total Pages 560
ISBN 9780849388699
Language English, Spanish, and French
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Book Summary:

This book addresses possible analogies between cancer and developmental biology. An international group of experts provides a multidisciplinary approach, allowing biological or clinical scientists involved with cancer research to integrate specific information from diverse areas. Five concepts of cancer are presented, and developmental biology is reviewed at five levels. These are integrated in discussions of failure in organisation as a basis of cancer and its control. The book will be a valuable reference for both newcomers as well as experienced biological and clinical scientists. Features

Developmental Biology of Neoplastic Growth by Alvaro Macieira-Coelho

Title Developmental Biology of Neoplastic Growth
Author Alvaro Macieira-Coelho
Publisher Springer Science & Business Media
Release 2006-03-30
Category Science
Total Pages 254
ISBN 3540276718
Language English, Spanish, and French
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Book Summary:

In this book, tumour growth is perceived as a deviation from the normal development of the human organism. The molecular, cellular, and tissue determinants of different tumours are discussed showing that each is a different disease, often corresponding to a particular developmental stage. The natural history of several cancers illustrates how clinical incidence can be just the visible part of the iceberg, while the first changes at the tissue level sometimes occur several years before tumour growth becomes manifest. Several mechanisms are proposed to explain the distribution of cancers during the human life span and the decline of the incidence of cancers during human senescence.

Title The Cell Surface in Development and Cancer
Author Malcolm S. Steinberg
Publisher Springer Science & Business Media
Release 2013-06-29
Category Science
Total Pages 364
ISBN 1468450506
Language English, Spanish, and French
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Book Summary:

This series was established to create comprehensive treatises on specific topics in developmental biology. Such volumes serve a useful role in developmental biology, since it is a very diverse field that receives contributions from a wide variety of disciplines. This series is a meeting-ground for the various practi tioners of this science, facilitating an integration of heterogeneous information on specific topics. Each volume is intended to provide the conceptual basis for a comprehen sive understanding of its topic as well as an analysis of the key experiments upon which that understanding is based. The specialist in any aspect of devel opmental biology should understand the experimental background of the field and be able to place that body of information in context to ascertain where additional research would be fruitful. At that point, the creative process gener ates new experiments. This series is intended to be a vital link in that ongoing process of learning and discovery.

Developmental Biology and Cancer by Phillip A. Sharp

Title Developmental Biology and Cancer
Author Phillip A. Sharp
Publisher
Release 1999
Category
Total Pages
ISBN
Language English, Spanish, and French
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Book Summary:

Title Cancer and Development
Author
Publisher Academic Press
Release 2011-02-28
Category Medical
Total Pages 384
ISBN 9780123809162
Language English, Spanish, and French
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Book Summary:

In recent years, a number of molecular pathways and cellular processes that are essential for normal vertebrate development have been implicated in cancer initiation and progression. In this volume, leaders in the field of cancer genetics and developmental biology share recent insights into the importance of developmental pathways for tumorigenesis. These discoveries provide important avenues for innovative new approaches to treating some of the most challenging developmental tumors. Provides researchers an overview and synthesis of the latest research findings and contemporary thought in the area There are now a large number of molecular targeted therapies for the treatment of cancer. Many of these therapies target pathways that are essential for normal development. Therefore, this volume provides an up-to-date and timely perspective on those pathways and biological processes that hold the greatest promise for targeted intervention.

Targeting Notch in Cancer by Lucio Miele

Title Targeting Notch in Cancer
Author Lucio Miele
Publisher Springer
Release 2018-11-23
Category Medical
Total Pages 389
ISBN 149398859X
Language English, Spanish, and French
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Book Summary:

The serendipitously discovered link between developmental biology and cancer, touched of an explosion of discoveries on the role of Notch in human malignancies, including every aspect of cancer biology, from control of differentiation, proliferation and apoptosis in transformed cells to angiogenesis, tumor-stroma interaction and anti-cancer immune responses. A number of observations have revealed that Notch even plays a role in the renewal of cancer stem cells and tumor initiating cells, which are thought to be a major cause of resistance to treatment. Targeting Notch in Cancer will provide researchers, oncologists, pharmacologists and students with a detailed understanding of the intricate cross-talk between Notch and other pathways of therapeutic interest so to better design rational drug combinations for specific diseases and disease subsets. Divided into two parts, Part I describes in detail what we know about the genetics, molecular biology, biochemistry and structural biology of Notch, as well as the role of Notch in such processes as angiogenesis and immune surveillance. Without insights gained from these basic studies, rational targeting of Notch in human disease would be impossible. Part II describes the role of Notch and ongoing experimental therapeutic efforts in the most important subtypes of human cancers, organized in a clinically oriented fashion by organs and systems affected

Title Cancer and Development
Author
Publisher Academic Press
Release 2011-03-28
Category Medical
Total Pages 384
ISBN 9780123809179
Language English, Spanish, and French
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Book Summary:

In recent years, a number of molecular pathways and cellular processes that are essential for normal vertebrate development have been implicated in cancer initiation and progression. In this volume, leaders in the field of cancer genetics and developmental biology share recent insights into the importance of developmental pathways for tumorigenesis. These discoveries provide important avenues for innovative new approaches to treating some of the most challenging developmental tumors. Provides researchers an overview and synthesis of the latest research findings and contemporary thought in the area There are now a large number of molecular targeted therapies for the treatment of cancer. Many of these therapies target pathways that are essential for normal development. Therefore, this volume provides an up-to-date and timely perspective on those pathways and biological processes that hold the greatest promise for targeted intervention.