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Title Free Radicals in Chemistry and Biology
Author Milan Lazar
Publisher CRC Press
Release 1989-03-31
Category Science
Total Pages 322
ISBN 9780849353871
Language English, Spanish, and French
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Book Summary:

Elementary radical reactions are described in terms of fundamental knowledge of organic chemistry and chemical physics in this valuable reference text. The complex radical processes of nonchain and chain mechanisms, such as dimerization, alkylation, polymerization, telomerization, halogenation pyrolysis, oxidation and combustion, are complemented by reactions in chemical lasers and in the cosmos, as well as by reactions in biological objects under normal or pathological metabolism. The text also provides the synthesis of facts from various fields of research and involves mechanisms where free radicals appear either as main or side intermediates in one of the several alternatives of the reaction pathway. Highlights include 38 tables and 39 figures.

Title Free Radicals in Biology and Environment
Author F. Minisci
Publisher Springer Science & Business Media
Release 1997-03-31
Category Science
Total Pages 520
ISBN 9780792345022
Language English, Spanish, and French
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Book Summary:

Our understanding of the quantitative aspects of free radical chemistry and the involvement of radicals in such areas as biology, medicine, the environment, etc., has developed spectacularly over recent years, yet the various topics are commonly discussed separately, in specific meetings and specialised publications. Free Radicals in Biology and Environment draws together two important areas of free radical chemistry, using as a bridge the fundamental physical chemistry of free radicals (spectroscopic detection of free radicals, evaluation of absolute rate constants, elucidation of mechanisms of free radical reactions and catalysis, photochemical and radiation processes, etc.). The most relevant topics covered are the EPR detection of radicals in biochemical systems and in pollutant formation and degradation, oxidation processes in biology and in the troposphere, radiation and induced damage, and atmospheric pollutants arising from incomplete combustion. Also covered are the chemistry and biochemistry of nitric oxide and peroxynitrite, the chemistry and biochemistry of DNA radicals, the role of radicals in myeloperoxidase, lignineperoxidase, radicals and cardiovascular injury, radiation and the fragmentation of cells and tissues.

Title Free Radicals Oxidative Stress and Antioxidants
Author Tomris Özben
Publisher Springer Science & Business Media
Release 1998-04-30
Category Science
Total Pages 416
ISBN 9780306458132
Language English, Spanish, and French
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Book Summary:

There has been an explosion of research related to free radicals and antioxidants in recent years, and hundreds of laboratories worldwide are actively involved in many as pects of free radicals, oxidative stress, and antioxidants. The literature on these topics in creases exponentially every year. Over the last few years, we have been fortunate to witness a widespread recognition of the important role of free radicals in a wide variety of pathological conditions including diseases such as atherosclerosis, cardiovascular and neurological diseases, ischemia, emphysema, diabetes, radiation injury, cancer, etc. In ad dition, many laboratories are studying the role of free radicals in the inexorable process of aging. Increased evidence involves free radicals with the etiology of various diseases, thereby suggesting the use of antioxidants as a viable therapeutic approach for the treat ment of free radical mediated pathologies. Despite these impressive developments, many important aspects of free radical and antioxidant research are open for investigation. It is important to understand the overall mechanisms involved in free radical mediated physiological and pathological conditions. This knowledge will undoubtedly lead to the development of new therapeutic approaches to prevent or control free radical related diseases. This book contains the proceedings of the NATO Advanced Study Institute (ASI) on "Free Radicals, Oxidative Stress, and Antioxidants: Pathological and Physiological Sig nificance," which was held in Antalya, Turkey from May 24-June 4, 1997.

Oxygen Free Radicals in Shock by Gian Paolo Novelli

Title Oxygen Free Radicals in Shock
Author Gian Paolo Novelli
Publisher S Karger Ag
Release 1986
Category Medical
Total Pages 248
ISBN
Language English, Spanish, and French
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Book Summary:

Free Radicals in Biology by William Pryor

Title Free Radicals in Biology
Author William Pryor
Publisher Elsevier
Release 2012-12-02
Category Science
Total Pages 468
ISBN 0323149316
Language English, Spanish, and French
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Book Summary:

Free Radicals in Biology, Volume VI covers the significant biological implications of arachidonic acid chemistry in free radical biology. This 11-chapter volume explores the biochemistry of the prostaglandins, leukotrienes, and other products from arachidonic acid. The introductory chapters describe the chemistry of the eicosanoids; the structures of prostaglandin and leukotriene compounds; the role of lipid hydroperoxides in controlling prostaglandin biosynthesis; and the oxidation of xenobiotics during prostaglandin H biosynthesis. The discussion then shifts to the effects of the so-called fatty acid paradoxes on cell proliferation, tumorigenesis, and metastasis, followed by chapters on arachidonic acid cascade process; the causes of lung injury conditions, such as hyperoxia; and the origin of low-level chemiluminescence in cells. This volume further deals with the oxy-radical involvement in parasitic diseases and the mechanisms for activation of aromatic amine carcinogens. The concluding chapters examine the controversial one- and two-electron mechanisms for activation of polynuclear hydrocarbon carcinogens and a hypothesis to rationalize the effects of radicals on the life span of mammals. These chapters propose that aging results from toxic by-products of metabolism, and longevity is determined by the ability of an organism to deal with these products. This book will be of great benefit to biochemists, biologists, and physicists.

Title Free Radicals in ENT Pathology
Author Josef Miller
Publisher Humana Press
Release 2015-04-30
Category Science
Total Pages 507
ISBN 3319134736
Language English, Spanish, and French
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Book Summary:

This comprehensive volume examines the current state of free radical biology and its impact on otology, laryngology, and head and neck function. The chapters collectively highlight the interrelationship of basic and translational studies in each area, define the challenges to translation, and identify the existing basic issues that demand investigation as well as the opportunities for novel intervention to prevent and treat ENT pathology and impairment. In each chapter, or in some cases pairs of chapters, the author(s) have included or married issues of basic research with translational challenges and research, thus defining the pathway by which new basic insights may lead to interventions to prevent or treat impairment. The final chapter of this book reflects a meeting of all the contributors, culminating in a discussion and “white paper” that identifies the challenges to the field and defines the studies and collaborations that may lead to improved understanding of free radical biology in ENT and, subsequently, new interventions to medically treat ENT pathology.

Title Trace Elements Micronutrients and Free Radicals
Author Ivor E. Dreosti
Publisher Springer Science & Business Media
Release 2012-12-06
Category Science
Total Pages 231
ISBN 1461204194
Language English, Spanish, and French
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Book Summary:

This book addresses many of today's key issues pertaining to free radical damage and micronutrient production. A valuable guide for a variety of specialists concerned with nutrition and the prevention of free radical tissue injury.

Title Formation and Trapping of Free Radicals
Author Arnold Marvin Bass
Publisher
Release 1960
Category Radicals (Chemistry).
Total Pages 548
ISBN
Language English, Spanish, and French
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Book Summary:

History of radical trapping / F.O. Rice -- Radical formation and trapping from the gas phase / B.A. Thrush -- Techniques of electrical discharge for radical production / Thomas M. Shaw -- Radical formation and trapping in the solid phase / George C. Pimentel -- Low temperature equipment and techniques / F.A. Mauer -- Optical spectroscopy of trapped radicals / D.A Ramsay -- Electron spin resonance studies of trapped radicals / C.K. Jen -- Chemical and physical studies of trapped radicals / James W. Edwards -- X-ray diffraction studies and their crystal-chemical implications / H.S. Peiser -- Free radical trapping - theoretical aspects / J.L. Jackson -- Trapped radicals in astrophysics / Bertram Donn -- Trapped radicals in high polymer systems / H. Morawetz -- Trapped radicals in propulsion / Maurice W. Windsor -- Trapped radicals in radiation damage / R.S. Alger -- Trapped radicals in biological processes / C.H. Bamford and A.D. Jenkins -- Chemical utilization of trapped radicals / D.E. Carr.

Title Free Radicals in Diagnostic Medicine
Author Donald Armstrong
Publisher Springer Science & Business Media
Release 2012-12-06
Category Medical
Total Pages 464
ISBN 1461518334
Language English, Spanish, and French
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Book Summary:

An International Syaposiua on Free Radicals in Diagnostic Medicine was co-sponsored by the state University of New York at Buffalo, Roswell Park Cancer Institute, and the Upstate NY Section of the American Association of Clinical Chemistry. The theme was "A Systems Approach To Laboratory Technology, Clinical Correlations And Antioxidant Therapy." The symposium was held on October 7-8, 1993 at the Hyatt Hotel and on October 9 at Roswell Park Cancer Institute, Buffalo, New York. This proceedings volume contains chapters from platform presentations, poster sessions and from invited special lectures in the areas of basic science, clinical applications and efficacy of treatment. A Special Lecture on the relevance of free radical analysis to clinical medicine was presented by Professor Kunio Yagi of Japan. The Yagi procedure to measure thiobarbituric acid (TBA) reaction reflects the amount of reactive substances, lipid peroxides and aldehydes, in the sample. For example, normal subjects will have less than 4 nmol/ml of serum lipid peroxides, while a person with diabetes generally has equal or greater than 5.0 and a diabetic person with vascular complications often exceeds 7.5 nmol/ml. Serum TBA is a clinically important measure that relates to aging, gender and estrogen as an antioxidant, in the prognosis for vascular disorders, and in pathological conditions relative to the amount of lipid peroxidation. The BASIC SCIENCES portion of the program examined: "Mechanisms of Action, Pathophysiology and Laboratory Tests" in six presentations.

Title Free Radicals from Basic Science to Medicine
Author POLI
Publisher Birkhäuser
Release 2013-03-11
Category Science
Total Pages 530
ISBN 3034891164
Language English, Spanish, and French
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Book Summary:

Free radical-mediated reactions have been well known in chemistry and physical chemistry for many years. Applying this knowledge to living organisms, biochemists have shown that reactive free radicals are formed at many intracellular sites during normal metabolism, and they have started to suggest possible roles in various pathological processes and conditions, for example in radiation damage, in the metabolism of xenobiotics, in carcinogenesis and in metabolic disorders. At present, a large and relevant mass of experimental evidence supports the view that reactive free radicals are involved in the pathogenesis of several diseases and syndromes. This literature has captured the attention and interest of people involved in the biomedical field. Exciting developments in radical research are probable in the near future, establishing a greater interaction between basic science research and medicine. While the task of defining the involvement of free radicals in human pathology is difficult, it is nonetheless extremely important that such interaction be fulfilled as soon as possible. These were the considerations motivating us during the organization of the VI Biennial Meeting of the International Society for Free Radical Research held in Torino, Italy, in June 1992, and also during the preparation of this book. Experts in the various aspects of free radical research were invited to participate in the Torino Meeting and to contribute chapters for this volume.