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Metastatic Diseases by Sandeep Arora

Title Metastatic Diseases
Author Sandeep Arora
Publisher CRC Press
Release 2021-11-18
Category Medical
Total Pages 316
ISBN 100006493X
Language English, Spanish, and French
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Book Summary:

This insightful volume opens new horizons for exploring modern therapeutic entities and emerging targets for combating the deadly disease of cancer. The authors provide a review of cancer along with descriptions of its molecular level mechanisms and emphasize the role of promising new therapies, including herbal therapies, that can be utilized for the treatment of metastatic diseases. The chapters look at specific approaches that have been researched and developed and that have almost reached the standardization stage, such as intracellular mechanisms, particularly phosphoprotein-enriched astrocytes and transthyretin proteins; CXCR4; autophagy-inhibiting drugs; spatiotemporal genetic analysis; tyrosine kinase inhibitors; and more. Also considered are advances in diagnostic systems like intra vital microscopy and molecular imaging.

Title Contemporary Management of Intracranial Metastatic Disease
Author Sunit Das
Publisher Frontiers Media SA
Release 2019-10-17
Category
Total Pages
ISBN 288963129X
Language English, Spanish, and French
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Book Summary:

The development of intracranial metastatic disease (IMD) complicates the course of 20% of patients with cancer. Despite improvements in patient survival with more aggressive treatment options as compared to the prior standard of palliative whole brain radiation, outcomes for patients who develop IMD remain dispiriting. There is need to celebrate our advances; but a major collaborative multidisciplinary effort is needed to push the field to achieve more meaningful survival benefits for our patients with IMD. In this Research Topic collection, we have assembled work detailing the latest innovations in brain metastases imaging and management, spanning from minimally invasive surgery to immunotherapy. We hope that you find it a valuable resource.

Title Metastatic Disease of the Nervous System
Author David Schiff
Publisher Elsevier
Release 2018-01-04
Category Medical
Total Pages 304
ISBN 0444638792
Language English, Spanish, and French
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Book Summary:

Metastatic Disease of the Nervous System, Volume 149, begins with an overview of the impact and range of direct neoplastic involvement of the central and peripheral nervous system, comprehensively reviewing all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy in their management, and the complications of these interventions. The clinical manifestations, diagnosis and treatment of leptomeningeal, dural, spinal epidural and plexus metastases are also covered in detail. Covers all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy Presents a multidisciplinary review of the evidence regarding accuracy of diagnostic testing and evidence-based reviews of therapies Addresses metastatic diseases of the nervous system for residents, fellows and clinicians in neurology and oncology

Metastatic Bone Disease by Ingo J. Diel

Title Metastatic Bone Disease
Author Ingo J. Diel
Publisher Springer Science & Business Media
Release 2012-12-06
Category Medical
Total Pages 186
ISBN 3642785964
Language English, Spanish, and French
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Book Summary:

"Metastatic Bone Disease: Fundamental and Clinical Aspects" is an expanded version of a workshop on bone metastases which was held in Heidelberg, Germany, in April 1993. Bone metastases very often develop from malignant tumors and lead to complications which considerably diminish the quality of life of the patient. Bone pain, pathological fractures, and hypercalcemic syndrome should be recognized and treated ear- ly, so as to prevent any further morbidity and immobilizati- on. Antiosteolytic substances such as biophosphonate can supplement the established palliative and supportive thera- pies. Highly qualified basic researchers and clinicians in pathophysiology, diagnosis, and treatment of metastatic bone disease have contributed to this book, providing a good overview ofpresent knowledge and research. The book will be of interest not only to specialists, but also to any physi- cian interested in oncology.

Liver and Pancreas by Denise Frias-Hidvegi

Title Liver and Pancreas
Author Denise Frias-Hidvegi
Publisher Igaku-Shoin Medical Publishers
Release 1988
Category Medical
Total Pages 332
ISBN
Language English, Spanish, and French
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Metastatic Bone Disease by R. Lor Randall

Title Metastatic Bone Disease
Author R. Lor Randall
Publisher Springer
Release 2015-12-01
Category Medical
Total Pages 368
ISBN 1461456622
Language English, Spanish, and French
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Book Summary:

Providing an integrated approach to the diagnosis and management of patients with metastatic bone disease (MBD), this comprehensive text combines discussion of the pathobiology of the disease with the latest oncological and orthopedic treatment modalities. After opening with an examination of the epidemiology and impact of MBD, the biology of bone metastases are discussed, along with considerations of the tissue of origin. Evaluation, biopsy and medical therapy, including metabolic agents and bio targeting. The heart of the book presents oncological approaches (supportive, radiation and interventional) and principles of orthopedic surgical oncology, with subsequent chapters covering specific anatomy, from the pelvis to the lower extremity and the spine. Chapters on emerging surgical technology and future directions conclude the text and redefine an integrated approach to patient care. Taken together, Metastatic Bone Disease is an excellent resource for orthopedic surgeons and cancer specialists alike.

Metastatic Spine Disease by Rex A. W. Marco

Title Metastatic Spine Disease
Author Rex A. W. Marco
Publisher Springer
Release 2018-05-24
Category Medical
Total Pages 307
ISBN 3319762524
Language English, Spanish, and French
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Book Summary:

This comprehensive text focuses exclusively on the management of metastatic spinal disease, evaluating the most recent literature and providing patient-centered treatment algorithms. Beginning with initial imaging, classification and clinical decision-making, the spine is approached anatomically from the upper cervical to the sacrum, describing the unique considerations and approaches appropriate to each region, such as laminectomy and stabilization, en bloc spondylectomy and resection and reconstruction. Less invasive and minimally invasive approaches are discussed throughout the text. Radiation therapy modalities and other adjuvant treatments are also discussed, as well as reconstructive flap coverage and the management of complications. The spinal column is the most common site of metastatic cancer, and a multidisciplinary approach is required to provide patients with reasonable management options to prevent and treat the disabling symptoms caused by this debilitating condition. This compendium of experience from thought leaders in the treatment of metastatic spine disease will provide spine surgeons, oncologists, radiation oncologists, physiatrists and palliative care specialists with up-to-date information to guide their patients through the multidisciplinary management of metastatic spinal disease.

Title Pulmonary Manifestations of Pediatric Diseases
Author Nelson L. Turcios
Publisher Elsevier Health Sciences
Release 2009
Category Medical
Total Pages 348
ISBN 141603031X
Language English, Spanish, and French
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Book Summary:

Pulmonary Manifestations of Pediatric Diseases is the first comprehensive, practical book strictly focused on diagnosing and treating the full spectrum of respiratory complications of non-pulmonary diseases. Pediatric pulmonologists and other expert specialists present their up-to-date and balanced perspectives on new approaches to therapy and recent advances on everything from HIV/AIDS and transplantation to postoperative complications. The contributors are some of the most distinguished and recognizable physicians in their fields giving you the benefit of accumulated insight and experience. You'll have everything you need to perform a complete pulmonary consultation in one handy reference. Details the key "need-to-know" facts for accurate diagnosis and therapy during pulmonary consultations. Provides the latest updates on rapidly-changing topics, including HIV/AIDS, transplantation, and postoperative pulmonary complications. Discusses current clinical controversies to provide perspectives on sensitive topics and offers the authors' preferred approaches whenever relevant. Features balanced coverage on each condition from a pediatric pulmonologist and other expert pediatric specialists.

Title Circulating Tumor Cells in Breast Cancer Metastatic Disease
Author Roberto Piñeiro
Publisher Springer Nature
Release 2020
Category Biomedical engineering
Total Pages 177
ISBN 3030358054
Language English, Spanish, and French
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Book Summary:

This book compiles the latest research and key findings about the role of circulating tumor cells (CTCs) in Breast Cancer progression, both from the research and clinical standpoint. Based on latest advancements, the content of the book is set out to provide a clear overview about the biology and use of CTCs as a tool for the monitoring and management of breast cancer patients. This work covers basic concepts about the process of metastasis, the biology of CTCs and their potential applications as a biomarker in breast cancer. It will enable readers to delve into the process of epithelial-mesenchymal plasticity (EMP), mechanisms and clinical implications of tumor cell dormancy and minimal residual disease, and into the phenotypical and molecular heterogeneity of CTCs and CTC clusters, including the epigenetic characterization of CTCs. Readers will find out about the key technologies used for the isolation of CTCs as well as the latest advances towards the characterization of CTCs, involving single cell analyses and patient-derived models. It will discuss the evidences about the use of CTCs as a tool to monitor breast cancer progression and therapy response, as well as to unravel mechanisms of resistance to therapy and to identify new therapeutic targets favoring the development of novel anticancer drugs. Lastly, it will discuss ongoing clinical trials and try to foresee the future of CTCs in terms of clinical application and implementation in the clinical routine. The topic of this book is particularly relevant for cancer researchers and oncologist with an interest in the field, looking to refresh or to broaden their knowledge and understanding about the use of CTCs as a diagnostic biomarker in breast cancer.

Title Experimental and Clinical Metastasis
Author Julia V. Burnier
Publisher Springer Science & Business Media
Release 2013-01-04
Category Medical
Total Pages 472
ISBN 1461436850
Language English, Spanish, and French
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Book Summary:

Metastatic disease is the most lethal aspect of human malignancies, making the understanding and continued research of the process of metastasis a crucial step in treating cancer. The proposed book, entitled “Experimental and Clinical Metastasis: A Comprehensive Review” aims to provide a clear and extensive review of the clinical and experimental implications of metastatic disease. This work focuses on recent contributions to the field of metastasis, and will highlight crucial findings in the molecular understanding of disseminated disease as well as standard and personalized medicine currently being investigated in the clinic. Topics will include, among many, gene properties of metastatic cells, molecular mechanisms of tumour growth and spread, animal models of metastasis, and clinical implications, markers and treatment for metastatic disease. With the participation of worldwide experts in the field of oncology, from major academic and government centres, this book will provide a leading manual for the study of the metastatic process, from benchside science to bedside care. In this light, the proposed book will facilitate classroom learning for both medical and graduate students, as well as serve as a tool for physicians and researchers interested in the metastatic process. In addition, this book will include the latest advances in basic science as well as leading technologies and theories of targeting metastatic cells. Most importantly, not only will basic and clinical aspects be discussed, but furthermore, the translational aspect of research in metastatic diseases will be emphasized.