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Tachykinins by Peter Holzer

Title Tachykinins
Author Peter Holzer
Publisher Springer Science & Business Media
Release 2012-12-06
Category Medical
Total Pages 569
ISBN 3642188915
Language English, Spanish, and French
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Book Summary:

The tachykinins represent one of the most thoroughly investigated family of neuropeptides, whose members and receptors have been characterized at the genetic and molecular level and whose pharmacology has now been advanced to the first clinical application. These exciting accomplishments and prospects are reviewed and discussed in this volume in an authoritative manner. Particular emphasis is laid on the development of selective non-peptide antagonists for all 3 tachykinin receptors and their potential as novel drugs in a variety of diseases. The approval of the first tachykinin receptor antagonist as an antiemetic drug is particularly highlighted, and the utility of tachykinin receptor antagonists in affective disorders, chronic obstructive airway disease and irritable bowel syndrome, to name a few indications, is extensively considered.

The Tachykinin Receptors by Stephen H. Buck

Title The Tachykinin Receptors
Author Stephen H. Buck
Publisher Springer Science & Business Media
Release 2012-12-06
Category Medical
Total Pages 630
ISBN 1461203015
Language English, Spanish, and French
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Book Summary:

Offers a state-of-the-art review by international experts on all aspects of tachykinin receptors, including neuropeptide/peptide and G-protein-linked receptors in general. It covers the physiology, pharmacology, biochemistry, and molecular biology of these receptors from both clinical and basic research points of view. Topics treated by the distinguished contributors include the characterization of tachykinin receptors, the mechanisms of tachykinin receptor action, a reflection on future prospects, and a historical consideration of tachykinin research.

Title Neurogenic Inflammation in Health and Disease
Author Gábor Jancsó
Publisher Elsevier
Release 2009
Category Medical
Total Pages 346
ISBN 0444532293
Language English, Spanish, and French
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Book Summary:

Morphological and functional studies revealed a complex system of primary sensory neurons which parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel which transmits pain. * Neurogenic inflammation in historical perspective * Cardiac protection by nociceptive afferents * Molecular mechanisms of nociception * Sensory mechanisms in migraine pathophysiology * Vagal signalling of visceral inflammation * Neurogenic mechanisms in arthritis * Therapeutic implications of vanilloid-type compounds

Title New Drugs for Asthma Allergy and COPD
Author Trevor T. Hansel
Publisher Karger Medical and Scientific Publishers
Release 2001-01-01
Category Medical
Total Pages 389
ISBN 3805568622
Language English, Spanish, and French
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Book Summary:

This book provides a state-of-the-art account by academic respiratory physicians and senior pharmaceutical industry personnel on the development of new drugs for asthma, allergy and COPD. It contains 80 chapters of highly condensed information, presented in an attractive, reader-friendly format with much use of tables, figures and diagrams. In addition to summarizing the diverse range of current approaches, this handbook also looks into the future, considering many topics that are promising, but have only emerged in the last few years. Developments within established drug categories such as beta-2-agonists, steroids and leukotriene antagonists are also reviewed. Never before has a single book brought together so many pharmaceutical drug developers sharing their experience on such a wide range of respiratory topics!

Title The Immune Neuroendocrine Circuitry
Author I. Berczi
Publisher Elsevier
Release 2003-08-14
Category Science
Total Pages 618
ISBN 0080542514
Language English, Spanish, and French
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Book Summary:

The book summarises the current understanding of the Nervous -, Endocrine and Immune systems with emphasis on shared mediators and receptors and functional interaction. In addition to the fundamental physiological and pathophysiological mechanisms, which are presented in detail, some clinically relevant subjects are also presented, such as inflammation, asthma and allergy, autoimmune disease, immunodeficiency and the acute phase response. • A comprehensive presentation of neuroimmune biology • Introduces the subject matter to the uninformed reader • Contains basic information, theoretical considerations and up-to-date clinical chapters • The clinical chapters will be helpful to practising physicians

Asthma and COPD by Peter J. Barnes

Title Asthma and COPD
Author Peter J. Barnes
Publisher Elsevier
Release 2009-03-19
Category Medical
Total Pages 896
ISBN 0080920608
Language English, Spanish, and French
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Book Summary:

The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. * Each chapter considers Asthma and COPD in side-by-side contrast and comparison – not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management * Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD * Most extensive reference to primary literature on both Asthma and COPD in one source. * Easy-to-read summaries of the latest advances alongside clear illustrations

Neuropsychopharmacology by Kenneth L. Davis

Title Neuropsychopharmacology
Author Kenneth L. Davis
Publisher Lippincott Williams & Wilkins
Release 2002
Category Medical
Total Pages 1964
ISBN 9780781728379
Language English, Spanish, and French
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Book Summary:

Thoroughly updated and completely reorganized for a sharper clinical focus, the Fifth Edition of this world-renowned classic synthesizes the latest advances in basic neurobiology, biological psychiatry, and clinical neuropsychopharmacology. The book establishes a critical bridge connecting new discoveries in molecular and cellular biology, genetics, and neuroimaging with the etiology, diagnosis, and treatment of all neuropsychiatric disorders. Nine sections focus on specific groups of disorders, covering clinical course, genetics, neurobiology, neuroimaging, and current and emerging therapeutics. Four sections cover neurotransmitter and signal transduction, emerging methods in molecular biology and genetics, emerging imaging technologies and their psychiatric applications, and drug discovery and evaluation. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC

Title Pathophysiology of the Enteric Nervous System
Author Robin Spiller
Publisher John Wiley & Sons
Release 2008-04-15
Category Medical
Total Pages 272
ISBN 0470760036
Language English, Spanish, and French
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Book Summary:

Over the last few years there have been huge advances made in our understanding of the interactions between the brain and the gut – the enteric nervous system. This book is particularly relevant in the understanding, diagnosis and management of irritable bowel syndrome – the most common functional disorder of the bowel. IBS has been diagnosed in 10-20% of adults in the US, and symptoms of IBS are responsible for more than 3 million visits to the physician in the US. This book is aimed at specialist gastroenterologists but also should be of interest for trainees and fellows in gastroenterology, as well as PCPs and GPs with an interest in this subject.

Title Neuropeptides in Respiratory Medicine
Author PeterJ. Barnes
Publisher Routledge
Release 2017-09-29
Category Science
Total Pages 720
ISBN 135142887X
Language English, Spanish, and French
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Book Summary:

""This outstanding resource offers comprehensive presentations of the latest basic knowledge and the most advanced research on neuropeptides of the respiratory tract covering the structure, receptors, molecular biology, and function of each important neuropeptide and examining how they relate to disease. Demonstrates the utility of immunohistochemistry, autoradiography, molecular biology, smooth muscle contraction, and glandular secretion for the study of neural function both in vitro and in vivo!